Rational identification and characterisation of peptide ligands for targeting polysialic acid

-8 polysialic acid for immuno-targeting tumor cells*

Identification and Rational Redesign of Peptide Ligands to CRIP1, A Novel Biomarker for Cancers

Cysteine-rich intestinal protein 1 (CRIP1) has been identified as a novel marker for early detection of cancers. Here we report on the use of phage display in combination with molecular modeling to identify a high-affinity ligand for CRIP1. Panning experiments using a circularized C7C phage library yielded several consensus sequences with modest binding affinities to purified CRIP1. Two sequenc...

identification of new peptide ligands for epidermal growth factor receptor using phage display technology

Rational and combinatorial design of peptide capping ligands for gold nanoparticles.

Based on protein folding considerations, a pentapeptide ligand, CALNN, which converts citrate-stabilized gold nanoparticles into extremely stable, water-soluble gold nanoparticles with some chemical properties analogous to those of proteins, has been designed. These peptide-capped gold nanoparticles can be freeze-dried and stored as powders that can be subsequently redissolved to yield stable a...

Tumor Cell Targeting Peptide Ligands Distinguishing through Color-Encoding Microarray